Gene: [19q13/KLK1] kallikrein 1 (renal/pancreas/salivary);
COM |
The product of previously mapped to Chr 19q ARS gene (prostata-specific antigen) was demonstrated to contain kallikrein-like domains and to show the proteolytic activity. Therefore it is registered in the HUGEN as a kallikrein-like protease, see GEM:19q133/KLKPS." |
FAG |
[1] Genes KLK1, KLK2 (GEM:19q133/KLK2), KLKPS, and KLK3 (GEM:04q35/KLK3) belong to the serine proteinase multigene superfamily." |
POL |
Polymorphism with respect to MspI restriction fragments is found (Hermens-1990)." |
REF |
LOC,GEN,EAG "Evans BA &: Biochemistry, 27, 3124-3129, 1988 PRO,POL "Hermens R &: NAR, 18, N1, 208, 1990 LOC,LIN,MAP "Schonk D &: CCG, 51, (HGM10), 1075, 1989a LOC,LIN,MAP "Schonk D &: Genomics, 4, N3, 384-396, 1989b |
KEY |
pep, horm |
CLA |
coding, basic |
LOC |
19 q13.3-.4 |
MIM |
MIM: 147910 |
EZN |
ENZYME: 3.4.21.35 |