Gene: [20p1/OT] oxytocin, prepro- (neurophysin I); [NP1 OXT ]

GEN

The gene length is 1.5 kb.

EVO

Genes OT/NP1 and AVP/NP2 show a considerable homology, have similar intron-exon structure (although OT/NP1 does not contain the third peptide found in AVP/NP2) and are linked in chr 20 within the genomic fragment HindIII-SstI about 12 kb in size. These two genes are transcribed from different strands (i.e., in opposite directions)."

REF

POL,MUT,ASS,PAT "Repaske DR &: J Clin Endocrinol Metab, 70, N3, 752-757, 1990
LIN,MAF "Sausville E &: JBC, 260, N18, 10236-10241, 1985
LOC,LIN "Summar ML &: Mol Endocrinol, 4, 947-950, 1990
CLO,GEN,SEQ "see FAM:HPH/20

SWI

SWISSPROT: P01178

KEY

neu, horm

CLA

coding, basic

LOC

20 pt-12.2

MIM

MIM: 167050

SYN

NP1 OXT

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