Gene: [20p1/OT] oxytocin, prepro- (neurophysin I); [NP1 OXT ]
GEN | The gene length is 1.5 kb. |
EVO | Genes OT/NP1 and AVP/NP2 show a considerable homology, have similar intron-exon structure (although OT/NP1 does not contain the third peptide found in AVP/NP2) and are linked in chr 20 within the genomic fragment HindIII-SstI about 12 kb in size. These two genes are transcribed from different strands (i.e., in opposite directions)." |
REF | POL,MUT,ASS,PAT "Repaske DR &: J Clin Endocrinol Metab, 70,
N3, 752-757, 1990 LIN,MAF "Sausville E &: JBC, 260, N18, 10236-10241, 1985 LOC,LIN "Summar ML &: Mol Endocrinol, 4, 947-950, 1990 CLO,GEN,SEQ "see FAM:HPH/20 |
SWI | SWISSPROT: P01178 |
KEY | neu, horm |
CLA | coding, basic |
LOC | 20 pt-12.2 |
MIM | MIM: 167050 |
SYN | NP1 OXT |