Gene: [21q223/CRYAA] crystallin, alpha A polypeptide; [CRYA1]
FAG | The family of main human eye lens proteins, crystallins, is subdivided into three types, alpha, beta, and gamma. Coding genes for alpha crystallins are mapped to chrs 21 and 11: GEM:21q223/CRYAA, GEM:11q2/CRYAB. Coding genes for beta crystallins are mapped to chrs 17 and 22: GEM:17q1/CRYBA1, GEM:22q1/CRYBA4, GEM:22q1/CRYBB2; GEM:22q1/CRYBB3. Most gamma crystallin genes and pseudogenes form a cluster in chr 2q3 (FAM:CRYG/02q3), and one of them is mapped to chr 3: GEM:03^/CRYGS." |
REF | FUN,STR,EVO "DeJong, Hendriks: J Mol Evol, 24, 121-129,
1986 LOC,PRO "Hawkins JW &: Hum Genet, 76, 375-380, 1987 PRO,SEQ,EVO "Jaworski CJ, Piatigorsky: Nature, 337, (23 Feb), 752-754, 1989 LOC,PRO "Quax-Jeuken &: CCG, 40, (HGM8), 727-728, 1985 FUN,STR,EVO "Wistow G: FEBS Lett, 181, 1-6, 1985 |
SWI | SWISSPROT: P02489 |
KEY | exce, eye |
CLA | coding, basic |
LOC | 21 q22.3 |
MIM | MIM: 123580 |
SYN | CRYA1 |
