Gene: [MHC1/06p2133] major histocompatibility complex, MHC, class I polypeptides; (HLAA HLAB HLAC HLAE HLAF HLAG HLAH HLAJ HLAK HLAL)

COM

Using in situ hybridization Morton et al. (1984) showed that genes for class I HLA determinants (HLA-A, -B, -C) are located in 6p21.3. Strachan-1987 reviewed the molecular genetics of class I HLA antigens."

FUN

Major histocompatibility complex (MHC) class I genes typically encode polymorphic peptide-binding chains that are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells."

REL

GEM:01q253/HLALS

REF

NOM "Bodmer JG &: Immunol Today, 11, 3-10, 1990
LOC,MAF,FAG "Morton CC &: PNAS, 81, 2816-2820, 1984
REV,GEN,STR,SEQ "Strachan T: Brit Med Bull, 43, 1-14, 1987
LOC,MAF,FAG "see also FAM:MHC/06p2133

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