Gene family: metallothioneins; (@MLT1 MLT2P MLTL1 MLTL2 MLTL3 MLTL4)


The metallothioneins are small cysteine-rich proteins that bind heavy metal ions such as zinc, cadmium, and copper with high affinity, and have been functionally implicated in heavy metal detoxification and radical scavenging."


Transcription of metallothionein genes is induced by exposure of cells to heavy metals. This induction is mediated by metal-responsive promoter elements (MREs) which bind MRE transcription factor (GEM:01p3/MTF1)."