Gene: [01p3/MTF1] metal-regulatory transcription factor 1; [MTF-1 ]

COM

By fluorescence in situ hybridization, Brugnera-1994 mapped the MTF1 gene to Chr 1p34-p32, with 1p33 as the most likely location."

FUN

A transcription factor MTF-1 binds to metal-responsive promoter elements and may participate in regulation metallothionein gene expression. It is critically involved in zinc induction of metallothionein genes (FAM:MLT/00.0) (Brugnera-1994)."

MOP

The MTF1 protein has 753 amino acids with 93% amino acid sequence identity to the mouse protein and has an extension of 78 amino acids at the C-terminus without counterpart in the mouse."

REF

COD,SEQ,EVO,LOC "Brugnera E &: NAR, 22, 3167-3173, 1994

KEY

trc

CLA

coding, basic

LOC

01 p34-32

MIM

MIM: 600172

SYN

MTF-1

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