Рис. OTC seq
Нуклеотидная и аминокислотная последовательности
орнитин транскарбамилазы (OTC) человека ATG CTG TTT AAT CTG AGG ATC CTG TTA AAC AAT GCA GCT TTT AGA met leu phe asn leu arg ile leu leu asn asn ala ala phe arg 15 AAT GGT CAC AAC TTC ATG GTT CGA AAT TTT CGG TGT GGA CAA CCA asn gly his asn phe met val arg asn phe arg cys gly gln pro 30 CTA CAA AAT AAA GTG CAG CTG AAG GGC CGT GAC CTT CTC ACT CTA leu gln asn lys val gln leu lys gly arg asp leu leu thr leu 45 AAA AAC TTT ACC GGA GAA GAA ATT AAA TAT ATG CTA TGG CTA TCA lys asn phe thr gly glu glu ile lys tyr met leu trp leu ser 60 GCA GAT CTG AAA TTT AGG ATA AAA CAG AAA GGA GAG TAT TTG CCT ala asp leu lys phe arg ile lys gln lys gly glu tyr leu pro 75 TTA TTG CAA GGG AAG TCC TTA GGC ATG ATT TTT GAG AAA AGA AGT leu leu gln gly lys ser leu gly met ile phe glu lys arg ser 90 ACT CGA ACA AGA TTG TCT ACA GAA ACA GGC TTA GCA CTT CTG GGA thr arg thr arg leu ser thr glu thr gly leu ala leu leu gly 105 GGA CAT CCT TGT TTT CTT ACC ACA CAA GAT ATT CAT TTG GGT GTG gly his pro cys phe leu thr thr gln asp ile his leu gly val 120 AAT GAA AGT CTC ACG GAC ACG GCC CGT GTA TTG TCT AGC ATG GCA asn glu ser leu thr asp thr ala arg val leu ser ser met ala 135 GAT GCA GTA TTG GCT CGA GTG TAT AAA CAA TCA GAT TTG GAC ACC asp ala val leu ala arg val tyr lys gln ser asp leu asp thr 150 CTG GCT AAA GAA GCA TCC ATC CCA ATT ATC AAT GGG CTG TCA GAT leu ala lys glu ala ser ile pro ile ile asn gly leu ser asp 165 TTG TAC CAT CCT ATC CAG ATC CTG GCT GAT TAC CTC ACG CTC CAG leu tyr his pro ile gln ile leu ala asp tyr leu thr leu gln 180 GAA CAC TAT AGC TCT CTG AAA GGT CTT ACC CTC AGC TGG ATC GGG glu his tyr ser ser leu lys gly leu thr leu ser trp ile gly 195 GAT GGG AAC AAT ATC CTG CAC TCC ATC ATG ATG AGC GCA GCG AAA asp gly asn asn ile leu his ser ile met met ser ala ala lys 210 TTC GGA ATG CAC CTT CAG GCA GCT ACT CCA AAG GGT TAT GAG CCG phe gly met his leu gln ala ala thr pro lys gly tyr glu pro 225 GAT GCT AGT GTA ACC AAG TTG GCA GAG CAG TAT GCC AAA GAG AAT asp ala ser val thr lys leu ala glu gln tyr ala lys glu asn 240 GGT ACC AAG CTG TTG CTG ACA AAT GAT CCA TTG GAA GCA GCG CAT gly thr lys leu leu leu thr asn asp pro leu glu ala ala his 255 GGA GGC AAT GTA TTA ATT ACA GAC ACT TGG ATA AGC ATG GGA CAA gly gly asn val leu ile thr asp thr trp ile ser met gly gln 270 GAA GAG GAG AAG AAA AAG CGG CTC CAG GCT TTC CAA GGT TAC CAG glu glu glu lys lys lys arg leu gln ala phe gln gly tyr gln 285 GTT ACA ATG AAG ACT GCT AAA GTT GCT GCC TCT GAC TGG ACA TTT val thr met lys thr ala lys val ala ala ser asp trp thr phe 300 TTA CAC TGC TTG CCC AGA AAG CCA GAA GAA GTG GAT GAT GAA GTC leu his cys leu pro arg lys pro glu glu val asp asp glu val 315 TTT TAT TCT CCT CGA TCA CTA GTG TTC CCA GAG GCA GAA AAC AGA phe tyr ser pro arg ser leu val phe pro glu ala glu asn arg 330 AAG TGG ACA ATC ATG GCT GTC ATG GTG TCC CTG CTG ACA GAT TAC lys trp thr ile met ala val met val ser leu leu thr asp tyr 345 TCA CCT CAG CTC CAG AAG CCT AAA TTT TGA ser pro gln leu gln lys pro lys phe ter
