Биология и медицина

Рис. 19 pat

Нуклеотидная и аминокислотная
       последовательности (BCKDHA) альфа-субъединицы
      дегидрогеназы кетокислот с разветвленной цепью

                                             ttggttagcc aag

atg gcg gta gcg atc gct gca gcg agg gtc tgg cgg cta aac cgt
met ala val ala ile ala ala ala arg val trp arg leu asn arg  15

ggt ttg agc cag gct gcc ctc ctg ctg ctg cgg cag cct ggg gct
gly leu ser gln ala ala leu leu leu leu arg gln pro gly ala  30

cgg gga ctg gct aga tct cac ccc ccc agg cag cag cag cag ttt
arg gly leu ala arg ser his pro pro arg gln gln gln gln phe  45

tca tct ctg gat gac aag ccc cag ttc cca ggg gcc tcg gcg gag
ser ser leu asp asp lys pro gln phe pro gly ala ser ala glu  60

ttt ata gat aag ttg gaa ttc atc cag ccc aac gtc atc tct gga
phe ile asp lys leu glu phe ile gln pro asn val ile ser gly  75

atc ccc atc tac cgc gtc atg gac cgg caa ggc cag atc atc aac
ile pro ile tyr arg val met asp arg gln gly gln ile ile asn  90

ccc agc gag gac ccc cac ctg ccg aag gag aag gtg ctg aag ctc
pro ser glu asp pro his leu pro lys glu lys val leu lys leu 105

tac aag agc atg aca ctg ctt aac acc atg gac cgc atc ctc tat
tyr lys ser met thr leu leu asn thr met asp arg ile leu tyr 120

gag tct cag cgg cag ggc cgg atc tcc ttc tac atg acc aac tat
glu ser gln arg gln gly arg ile ser phe tyr met thr asn tyr 135

ggt gag gag ggc acg cac gtg ggg agt gcc gcc gcc ctg gac aac
gly glu glu gly thr his val gly ser ala ala ala leu asp asn 150

acg gac ctg gtg ttt ggc cag tac cgg gag gca ggt gtg ctg atg
thr asp leu val phe gly gln tyr arg glu ala gly val leu met 165

tat cgg gac tac ccc ctg gaa cta ttc atg gcc cag tgc tat ggc
tyr arg asp tyr pro leu glu leu phe met ala gln cys tyr gly 180

aac atc agt gac ttg ggc aag ggg cgc cag atg cct gtc cac tac
asn ile ser asp leu gly lys gly arg gln met pro val his tyr 195

ggc tgc aag gaa cgc cac ttc gtc act atc tcc tct cca ctg gcc
gly cys lys glu arg his phe val thr ile ser ser pro leu ala 210

acg cag atc cct cag gcg gtg ggg gcg gcg tac gca gcc aag cgg
thr gln ile pro gln ala val gly ala ala tyr ala ala lys arg 225

gcc aat gcc aac agg gtc gtc atc tgt tac ttc ggc gag ggg gca
ala asn ala asn arg val val ile cys tyr phe gly glu gly ala 240

gcc agt gag ggg gac gcc cat gcc ggc ttc aac ttc gct gcc aca
ala ser glu gly asp ala his ala gly phe asn phe ala ala thr 255

ctt gag tgc ccc atc atc ttc ttc tgc cgg aac aat ggc tac gcc
leu glu cys pro ile ile phe phe cys arg asn asn gly tyr ala 270

atc tcc acg ccc acc tct gag cag tat cgc ggc gat ggc att gca
ile ser thr pro thr ser glu gln tyr arg gly asp gly ile ala 285

gca cga ggc ccc ggg tat ggc atc atg tca atc cgc gtg gat ggt
ala arg gly pro gly tyr gly ile met ser ile arg val asp gly 300

aat gat gtg ttt gcc gta tac aac gcc aca aag gag gcc cga cgg
asn asp val phe ala val tyr asn ala thr lys glu ala arg arg 315

cgg gct gtg gca gag aac cag ccc ttt ctc atc gag gcc atg acc
arg ala val ala glu asn gln pro phe leu ile glu ala met thr 330

tac agg atc ggg cac cac agc acc agt gac gac agt tca gcg tac
tyr arg ile gly his his ser thr ser asp asp ser ser ala tyr 345

cgc tcg gtg gat gag gtc aat tac tgg gat aaa cag gac cac ccc
arg ser val asp glu val asn tyr trp asp lys gln asp his pro 360

atc tcc cgg ctg cgg cac tat ctg ctg agc caa ggc tgg tgg gat
ile ser arg leu arg his tyr leu leu ser gln gly trp trp asp 375

gag gag cag gag aag gcc tgg agg aag cag tcc cgc agg aag gtg
glu glu gln glu lys ala trp arg lys gln ser arg arg lys val 390

atg gag gcc ttt gag cag gcc gag cgg aag ccc aaa ccc aac ccc
met glu ala phe glu gln ala glu arg lys pro lys pro asn pro 405

aac ctg ctc ttc tca gac gtg tat cag gag atg ccc gcc cag ctc
asn leu leu phe ser asp val tyr gln glu met pro ala gln leu 420

cgc aag cag cag gag tct ctg gcc cgc cac ctg cag acc tac ggg
arg lys gln gln glu ser leu ala arg his leu gln thr tyr gly 435

gag cac tac cca ctg gat cac ttc gat aag tga gacctgctcagcccac
glu his tyr pro leu asp his phe asp lys ter

ccccacccatcctcagctaccccgagaggtagccccactctaaggggcgcagggggacct
gacagcacaccactgtcttccccagtcagctccctctaaaatactcagcggccagggcgg
ctgccactcttcacccctgctcctcccgtgttacattctcaggggacagcatctgcagca
gttgctgaggctccgtcagccccctcttcacctgttgttacagtgccttctcccaggggc
tgggtgatgggcacattcaggactagaagcccctctgggcatggggtggacatggcaggt
cagcctgtggaacttgcgcaggtgcgactggccagcagaggtcacgaataaactgcatct
ctgcgcctggctctct


		

Ссылки:
E1 альфа-Ген BCKDH комплекса