Биология и медицина

Рис. 20

Нуклеотидная и аминокислотная
        последовательности (BCKDHB) бета-субъединицы
       дегидрогеназы кетокислот с разветвленной цепью

                                                       gggg
atg gcg gtt gta gcg gcg gct gcc ggc tgg cta ctc agg ctc agg
met ala val val ala ala ala ala gly trp leu leu arg leu arg  15

gcg gca ggg gct gag ggg cac tgg cgt cgg ctt cct ggc gcg ggg
ala ala gly ala glu gly his trp arg arg leu pro gly ala gly  30

ctg gcg cgg ggc ttt ttg cac ccc gcc gcg act gtc gag gat gcg
leu ala arg gly phe leu his pro ala ala thr val glu asp ala  45

gcc cag agg cgg cag gtg gct cat ttt act ttc cag cca gat ccg
ala gln arg arg gln val ala his phe thr phe gln pro asp pro  60

gag ccc cgg gag tac ggg caa act cag aaa atg aat ctt ttc cag
glu pro arg glu tyr gly gln thr gln lys met asn leu phe gln  75

tct gta aca agt gcc ttg gat aac tca ttg gcc aaa gat cct act
ser val thr ser ala leu asp asn ser leu ala lys asp pro thr  90

gca gta ata ttt ggt gaa gat gtt gcc ttt ggt gga gtc ttt aga
ala val ile phe gly glu asp val ala phe gly gly val phe arg 105

tgc act gtt ggc ttg cga gac aaa tat gga aaa gat aga gtt ttt
cys thr val gly leu arg asp lys tyr gly lys asp arg val phe 120

aat acc cca ttg tgt gaa caa gga att gtt gga ttt gga atc gga
asn thr pro leu cys glu gln gly ile val gly phe gly ile gly 135

att gcg gtc act gga gct act gcc att gcg gaa att cag ttt gca
ile ala val thr gly ala thr ala ile ala glu ile gln phe ala 150

gat tat att ttc cct gca ttt gat cag att gtt aat gaa gct gcc
asp tyr ile phe pro ala phe asp gln ile val asn glu ala ala 165

aag tat cgc tat cgc tct ggg gat ctt ttt aac tgt gga agc ctc
lys tyr arg tyr arg ser gly asp leu phe asn cys gly ser leu 180

act atc cgg tcc cct tgg ggc tgt gtt ggt cat ggg gct ctc tat
thr ile arg ser pro trp gly cys val gly his gly ala leu tyr 195

cat tct cag agt cct gaa gca ttt ttt gcc cat tgc cca gga atc
his ser gln ser pro glu ala phe phe ala his cys pro gly ile 210

aag gtg gtt ata ccc aga agc cct ttc cag gcc aaa gga ctt ctt
lys val val ile pro arg ser pro phe gln ala lys gly leu leu 225

ttg tca tgc ata gag gat aaa aat cct tgt ata ttt ttt gaa cct
leu ser cys ile glu asp lys asn pro cys ile phe phe glu pro 240

aaa ata ctt tac agg gca gca gcg gaa gaa gtc cct ata gaa cca
lys ile leu tyr arg ala ala ala glu glu val pro ile glu pro 255

tac aac atc cca ctg tcc cag gcc gaa gtc ata cag gaa ggg agt
tyr asn ile pro leu ser gln ala glu val ile gln glu gly ser 270

gat gtt act cta gtt gcc tgg ggc act cag gtt cat gtg atc cga
asp val thr leu val ala trp gly thr gln val his val ile arg 285

gag gta gct tcc atg gca aaa gaa aag ctt gga gtg tct tgt gaa
glu val ala ser met ala lys glu lys leu gly val ser cys glu 300

gtc att gat ctg agg act ata ata cct tgg gat gtg gac aca att
val ile asp leu arg thr ile ile pro trp asp val asp thr ile 315

tgt aag tct gtg atc aaa aca ggg cga ctg cta atc agt cac gag
cys lys ser val ile lys thr gly arg leu leu ile ser his glu 330

gct ccc ttg aca ggc ggc ttt gca tcg gaa atc agc tct aca gtt
ala pro leu thr gly gly phe ala ser glu ile ser ser thr val 345

cag gag gaa tgt ttc ttg aac cta gag gct cct ata tca aga gta
gln glu glu cys phe leu asn leu glu ala pro ile ser arg val 360

tgt ggt tat gac aca cca ttt cct cac att ttt gaa cca ttc tac
cys gly tyr asp thr pro phe pro his ile phe glu pro phe tyr 375

atc cca gac aaa tgg aag tgt tat gat gcc ctt cga aaa atg atc
ile pro asp lys trp lys cys tyr asp ala leu arg lys met ile 390

aac tat tga ccatataggtaggtatgcatcttgagaaagctactatgtgcccctga
asn tyr ter

cattaacgtactgttaaccaagacacagcaatcatcagtgttttgatggtaacaaactt
tgatggtaaagttgataaaaggcaactttcagaagaaaataatgtgcttt


		

Ссылки:
E1 бета-Ген BCKDH комплекса