Практическое использование кровезаменителя: литература
Callas DD, Clark TL, Moriera PL, et al: In vitro effects of a novel hemoglobin-based oxygen carrier on the routine chemistry, therapeutic drug, coagulation, hematology, and blood bank assays. Clin Chem 43:1744,1997. This study reports how the presence of an HBOC solution in serum interfered with a variety of clinical assays.
Harringer W, Hodakowski GT, Svizzero, et al: Acute effects of massive transfusion of bovine hemoglobin blood substitute in a canine model of hemorrhagic shock. Eur J Cardiothorac Surg 6:649,1992. This study describes the effectiveness of an HBOC solution in resuscitation after major blood loss in dogs.
Moreira PL, Lansden CC, Clark TL, et al: Effect of Hemopure? on the performance of Ektachem and Hitachi clinical analyzers. Clin Chem 43:1790,1997. This technical brief describes the effects of an HBOC solution on serum chemistry tests with two commonly used analyzers.
Rentko VT, Wohl J, Murtaugh R, et al: A clinical trial of a hemoglobin-based oxygen carrier (HBOC) fluid in the treatment of anemia in dogs. J Vet Intern Med 10:177,1996. This abstract reports the efficacy and safety of an HBOC solution in a clinical trial in anemic dogs.
Standi T, Horn P, Wilhelm S, et al: Bovine hemoglobin is more potent than autologous red blood cells in restoring muscular tissue oxygenation after profound isovolaemic hemodilution in dogs. Can J Anaesth 43:714,1996. This report compares the effects of stored RBC, fresh blood, and an HBOC solution on hemodynamics and tissue oxygenation in dogs.
Teicher BA, Holden SA, Menon K, et al: Effect of hemoglobin solution on the response to intracranial and subcutaneous 9L tumors to antitumor alkylating agents. Cancer Chemother Pharmacol 33:7, 1993a. This report examined the effects of increasing the oxygenation of a solid tumor on the response of the tumor to alkylating agents.
Teicher BA, Schwartz GN, Sotomayor EA, et al: Oxygenation of tumors by a hemoglobin solution. J Cancer Res Clin Oncol 120:85, 1993b. This study evaluated the oxygen tensions of solid tumors in response to the administration of an HBOC solution while the subject was breathing various compositions of oxygen.
Vlahakes GJ, Lee R, Jacobs EE, et al: Hemodynamic effects and oxygen transport properties of a new blood substitute in a model of massive blood replacement. Eur J Cardiothorac Surg 100:379,1989. This report describes an exchange transfusion with an HBOC solution in awake sheep to a hematocrit of3%.
Walton RS: Polymerized hemoglobin versus hydroxyethyl starch in an experimental model of feline hemorrhagic shock. Proceedings of the 5th IVECC Symposium, 1996. This abstract reports the efficacy of an HBOC solution in resuscitation from hemorrhagic shock in cats.
