Gene: [01p36/FGR] tyrosine kinase v-fgr cell homolog; Gardner-Rasher feline sarcoma viral cell homolog;

COM

There are several functionally distinctive enzymes with the same EC:2.7.1.112 assigned (see GEM:01p361/EPHB2; GEM:05q21/FER)."

MAP

Loci: GEM:01p362/NPPA; GEM:01p3/ALPL; GEM:01p34/FUCA1; GEM:01p3/RHCE; GEM:01p32/MYCL1.
[1] pt-PND-ALPL-FUCA1-FGR-RH-D1S57-MYCL (Dracopoli-1988)."

FUN

[1] Systematic name: ATP:protein-tyrosine O-phosphotransferase.
[2] Reaction catalyzed: ATP + protein tyrosine = ADP + protein tyrosine phosphate."

FAG

There are many genes for various tyrosine kinases, some of which are closely related."

REF

FUN,PEP "Bishop JM: Annu Rev Biochem, 52, 301-354, 1983
EXP "Chen &: Nature, 319, 238-240, 1986
LOC,LIN,MAP "Dracopoli NC &: Genomics, 3, N2, 124-128, 1988
IDN,FUN,PEP "Gallis B &: PNAS, 78, 6689-6693, 1981
IDN,FUN,PEP "Hunter T, Sefton BM: PNAS, 77, N3, 1311-1315, 1980
CLO,COD,SEQ,EXP "Katamine S &: Mol Cell Biol, 8, 259-266, 1988
LOC,MOL "Le Beau MM &: AJHG, 36, S32, 1984a
LOC,MOL "Le Beau MM &: Nature, 312, 70-71, 1984b
CLO,SEQ,EXP,LOC "Nishizawa M &: Mol Cell Biol, 6, 511-517, 1986
CLO,SEQ,EXP,LOC "Parker RC &: Mol Cell Biol, 5, 831-838, 1985
CLO,SEQ,EXP,LOC "Tronick SR &: PNAS, 82, N19, 6595-6599, 1985
IDN,FUN,PEP "Van Tan H &: Eur J Biochem, 172, N1, 67-72, 1988

KEY

onc

CLA

coding, basic

LOC

01 p36.2-.1

MIM

MIM: 164940

EZN

ENZYME: 2.7.1.112

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