Gene: [03q2/RBPC1] retinol-binding protein 1, cellular; [CRBP1 RBP1]

FUN

About the functions of retinol derivatives, see Chytil, Ong: in 'The Retinoids', eds Sporn MB et al, vol 2, 90-125, Acad Press, Orlando, 1984."

FAG

Retinol-binding proteins are components of a multigene family, which comprises about 10 genes in human. These genes code for:
(1) fatty acid-binding proteins GEM:02p11/FAB1, GEM:04q/FAB2;
(2) retinol-, retinoic acid-, and retinaldehyde-binding proteins: GEM:03q2/RBPC1, GEM:03q2/RBPC2, GEM:10q112/RBPI1, GEM:10q241/RBPI2, GEM:15q24/RABPC1, GEM:01q213/RABPC2;
(3) an adipocyte- and mielin-specific P2 proteins."

PRO

?: ?/PstI/BamHI/0.6

POL

TaqI: A1= 3.0 kb (f= 0.55); A2= 2.7 (0.45)

REF

LOC,MOL "Colantuoni V &: CCG, 43, 221-222, 1986
CLO,SEQ,EXP "Colantuoni V &: BBRC, 130, 431-439, 1985
SEQ,EAG "Crabb JW &: JBC, 263, N35, 18678-18687, 1988a
SEQ,EAG "Crabb JW &: JBC, 263, N35, 18688-18692, 1988b
GEN,SEQ,EXP,LOC "Nilsson MHL &: Eur J Biochem, 173, 35-44, 1988a
GEN,SEQ,EXP,LOC "Nilsson MHL &: Eur J Biochem, 173, 45-51, 1988b
FUN "Ong DE: Arch Derm, 123, 1693-1695, 1987
PRO,POL "Pellegrino A &: NAR, 16, 7758, 1988
LOC,MOL "Rocchi &: Somat Cell Mol Genet, 15, 185-190, 1989

KEY

vit, trp

CLA

coding, basic

LOC

03 q21-22

MIM

MIM: 180260

SYN

CRBP1 RBP1

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