Gene: [05q31/IL13] interleukin 13; [P600 ]
COM | Smirnov-1995 showed that the IL13 gene is located 12 kb upstream from the IL4 gene (GEM:05q31/IL4) in a tail-to-head orientation and discussed the similarities between the 2 genes in their organization." |
FUN | Interleukin 13 is a cytokine secreted by activated T lymphocytes that shares many, but not all, biological activities with interleukin 4 (GEM:05q31/IL4). These overlapping activities are probably due to the existence of common receptor components, see GEM:0X^/IL13RA1 and GEM:0Xq24/IL13RA2." |
REF | PRO,COD,EXP "McKenzie
AN &: J Immunol, 150, 5436-5444, 1993 CLO,EXP "Morgan JG &: NAR, 20, 5173-5179, 1992 PRO,LOC,FAG "Smirnov DV &: Gene, 155, 277-281, 1995 |
SWI | SWISSPROT: P35225 |
KEY | imm, cyk, ont |
CLA | coding, basic |
LOC | 05 q31 |
MIM | MIM: 147683 |
SYN | P600 |
