Gene: [05q31/IL13] interleukin 13; [P600 ]

COM

Smirnov-1995 showed that the IL13 gene is located 12 kb upstream from the IL4 gene (GEM:05q31/IL4) in a tail-to-head orientation and discussed the similarities between the 2 genes in their organization."

FUN

Interleukin 13 is a cytokine secreted by activated T lymphocytes that shares many, but not all, biological activities with interleukin 4 (GEM:05q31/IL4). These overlapping activities are probably due to the existence of common receptor components, see GEM:0X^/IL13RA1 and GEM:0Xq24/IL13RA2."

REF

PRO,COD,EXP "McKenzie AN &: J Immunol, 150, 5436-5444, 1993
CLO,EXP "Morgan JG &: NAR, 20, 5173-5179, 1992
PRO,LOC,FAG "Smirnov DV &: Gene, 155, 277-281, 1995

SWI

SWISSPROT: P35225

KEY

imm, cyk, ont

CLA

coding, basic

LOC

05 q31

MIM

MIM: 147683

SYN

P600

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