Gene: [08q241/MYC] avian myelocytomatosis viral oncogene homolog;

FAG

Several other components of this family have been identified in the human genome (GEM:01p32/MYCL1; GEM:0Xq2/MYCL2; GEM:07p15/MYCLK1; and GEM:02p241/MYCN). Also identified is myc activator gene, functionally related with them (the gene is located in the same Chr 8 segment; see GEM:08q241/MYCA)."

EAG

Other components of the myc family were identified (cloned and mapped) in the rodent genome. These are b-myc (MIM:165210) and r-myc (MIM:165290), which was included in MIM as possible homologues of the corresponding human genes."

REF

PRO,LOC,CYG,FAG "Dalla-Favera R &: PNAS, 79, 7824-7827, 1982
REV,EVO,FAG "DePinho &: J Cell Biochem, 8, 3168-3174, 1988
PRO,SEQ,TRC,EXP,FUN "Iguchi-Ariga &: EMBO J, 7, N10, 3135-3142, 1988
PRO,LOC,CYG,FAG "Neel BG &: PNAS, 79, 7842-7846, 1982
PRO,LOC,CYG,FAG "Sakaguchi &: CCG, 37, (HGM7), 572-573, 1984
PRO,LOC,CYG,FAG "Taub R &: PNAS, 79, 7837-7841, 1982

SWI

SWISSPROT: P01106

KEY

onc, trc, repr

CLA

coding, basic

LOC

08 q24.12-.13

MIM

MIM: 190080

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