Gene: [10p112/TCF8] transcription factor 8; interleukin 2 inhibitor; zinc finger protein Nil-2-a; [Nil-2-a ]

FUN

TCF8 gene encodes a zinc finger transcription factor (Nil-2-a, negative regulator of IL2) that represses T-lymphocyte-specific interleukin-2 gene (GEM:04q2/IL2) expression by interacting with a negative regulatory domain within the IL2 gene promoter/enhancer."

REF

FUN "Franklin AJ &: Mol Cell Biol, 14, 6773-6788, 1994
LOC "Williams TM &: Genomics, 14, 194-196, 1992
CLO,SEQ "Williams TM &: Science, 254, 1791-1794, 1991

SWI

SWISSPROT: P37275

KEY

trc

CLA

coding, basic

LOC

10 p11.2

MIM

MIM: 189909

SYN

Nil-2-a

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