Gene: [04q2/IL2] interleukin 2 (T-cell growth factor); [TCGF ]

GEN

The gene length: 5.2 kb.

FAG

[1] Three interleukin 2 receptor types have been identified; alpha receptor gene is located in chromosome 10 (GEM:10p1/IL2RA), beta receptor one, in chromosome 22 (GEM:22q13/IL2RB), gamma receptor one, in chromosome X (GEM:0Xq131/IL2RG).
[2] On the localization of other human IL genes, see GEM:02q13/IL1A."

REL

GEM:17q25/ILF1.

REF

LIN,POL "Abbott CA &: Genomics, 9, 73-77, 1991
FUN,EXP "Brunvand &: JBC, 263, N35, 18904-18910, 1988
LIN,POL "Buetow KH &: AJHG, 48, 911-925, 1991
FUN,EXP "Cantrell, Smith: Science, 224, 1312-1316, 1984
CLO,SEQ,EXP "Clark SC &: PNAS, 81, 2543-2547, 1984
CLO,GEN,SEQ "Degrave W &: EMBO J, 2, 2349-2353, 1983
FUN,EXP "Depper &: PNAS, 82, 4230-4234, 1985
FUN,EXP "Efrat, Kaempfer: PNAS, 81, N9, 2601-2605, 1984
FUN,EXP "Fujita T &: Cell, 46, 401-407, 1986
CLO,GEN,SEQ "Fujita T &: PNAS, 80, (Dec), 7437-7441, 1983
IDN,PEP,FUN "Gillis &: Immunol Rev, 63, 167-209, 1982
REV,FUN,GEN,PAT "Greene WC: Clin Res, 35, N5, 439-450, 1987
CLO,GEN,SEQ "Holbrook NJ &: PNAS, 81, (Mar), 1634-1638, 1984
CLO,SEQ,EXP "Maeda S &: BBRC, 115, N3, 1040-1047, 1983
FUN,EXP "Matsui &: J Immunol, 142, N8, 2918-2923, 1989
LOC,FAG "Mita S &: BBRC, 138, N2, 966-973, 1986
CLO,GEN,SEQ "Mita S &: BBRC, 117, N1, 114-121, 1983
LIN,MAP "Murray JC &: AJHG, 42, 490-497, 1988
POG "Nakamura S &: Hum Genet, 71, 45-48, 1985
REV,FUN,MOL,MEB "Paetkau V: Can J Biochem Cell Biol, 63, 691-699, 1985
IDN,PEP,FUN "Robb, Smith: Mol Immunol, 18, 1087-1094, 1981
FUN,EXP "Rosenberg &: Science, 223, 1412-1415, 1984
PEP,SEQ,EVO,MAM,FAG "Schrader &: PNAS, 83, N8, 2458-2462, 1986
LOC,FAG "Seigel LJ &: Science, 223, 175-178, 1984
LOC,FAG "Shows TB &: Somat Cell Mol Genet, 10, N3, 315-318, 1984
FUN,EXP "Smith, Cantrell: PNAS, 82, 864-868, 1985
IDN,PEP,FUN "Stern &: PNAS, 81, 871-875, 1984
CLO,SEQ,EXP "Taniguchi T &: Nature, 302, (24 Mar), 305-310, 1983
POL,MUT,LIN "Weinberg K &: New Engl J Med, 322, 1718-1723, 1990
FUN,EXP "Williams &: J Immunol, 141, N2, 662-666, 1988
POG "Yuasa &: Hum Hered, 38, 91-94, 1988
POG "Zhou, Larsen: Hum Genet, 82, 393, 1989

SWI

 SWISSPROT: P01585

KEY

imm, cyk

CLA

coding, basic

LOC

04 q26-27

MIM

 MIM: 147680

SYN

TCGF

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