Gene: [11p155/TNNI2] troponin I2, skeletal, fast;

FUN

Troponin I is a constituent protein of the troponin complex located on the thin filament of striated (skeletal and cardiac) muscle and provided a calcium-sensitive switch for striated muscle contraction (see details in FAM:TNN/00.0). Troponin I binds actin (FAM:ACT/00.0) and inhibits actomyosin ATPase activity (FAM:MY/00.0) in the absence of calcium."

REL

GEM:11p155/TNNT3.

REF

LOC,FAG "Tiso N &: BBRC, 230, 347-350, 1997
SEQ "Zhu L &: BBA, 1217, 338-340, 1994

KEY

myo

CLA

coding, basic

LOC

11 p15.5

MIM

MIM: 191043

Ссылки: