Gene: [20q1/PLCG1] phospholipase C, gamma 1 (subtype 148);

EXP

A gene which product (G protein alpha 2 peptide) seemed to be a stimulator of phospholipase C activity was identified in chr 22: GEM:22q112/GNAZ."

EVO

A high homology between nucleotide sequences of the phospholipase C and protooncogene src mRNAs is revealed (Stahl-1988). The latter gene is mapped on the basis of proximity to PPLC1 (GEM:20q112/SRC)."

REL

GEM:00.0/PLCB2; GEM:11q13/PLCB3; 16q241/PLCG2.

REF

LOC,SEQ,EXP,MOP "Bristol A &: Cold Spring Harbor Symp, 53, 915-920, 1988
LOC,FAG,EAG,MOU,HUM "Lyu MS &: Mammal Genome, 7, N7, 501-504, 1996
CLO,SEQ,EVO "Stahl ML &: Nature, 332, 269-272, 1988

SWI

 SWISSPROT: P19174

KEY

lip

CLA

coding, basic

LOC

20 q12-13.1

MIM

 MIM: 172420

EZN

 ENZYME: 3.1.4.11

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