Gene: [00.0/PLCB2] phospholipase C, beta 2;

FUN

Phosphoinositide-specific phospholipase C acts as a signal transducer that generates 2 messengers, diacylglycerol and inositol 1,4,5-trisphosphate, by hydrolyzing inositol phospholipids."

FAG

The PLC family consists of four subfamilies:
[1] PLC-beta: GEM:00.0/PLCB2; GEM:11q13/PLCB3; GEM:20p12/PLCB4; see also GEM:20p12/PLCB1;
[2] PLC-gamma: GEM:20q1/PLCG1; GEM:16q241/PLCG2;
[3] PLC-delta: GEM:03p2/PLCD1;
[4] PLC-eta (or -epsilon): GEM:02q33/PLCE. See also GEM:03q2/PLD1."

REF

FAG,EAG,MOU,HUM "Lyu MS &: Mammal Genome, 7, N7, 501-504, 1996
COD,SEQ "Park D &: JBC, 267, 16048-16055, 1992

SWI

SWISSPROT: Q00722

KEY

lip

CLA

coding, basic

LOC

RS

MIM

?

EZN

ENZYME: 3.1.4.11

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