Gene: [02q3/ITGAV] integrin, alpha V (antigen CD51); vitronectin receptor, alpha polypeptide; [CD51 VNRA ]
MOP | Vitronectin receptor belongs to the integrins (see FAM:ITG/00.0) and consists of 2 major subunits: a 150kD alpha subunit and a 115-kD beta subunit. Alpha V associates with either the beta 1, beta 3, beta 5 or beta 6. Alpha subunit is composed of an heavy and light chains." |
FAG | Vitronectin is mapped to Chr 17q11 (see GEM:17q11/VTN). |
REF | CLO,SEQ,EXP,EVO "Cheresh DA &: Cell, 57, 59-69, 1989 LOC "Fernandez-Ruiz E &: CCG, 62, 26-28, 1993 CLO,SEQ,EXP,EVO "Fitzgerald LA &: Biochemistry, 26, 8158-8165, 1987 FUN,MOP "Polack &: Blood, 73, N6, 1519-1524, 1989 LOC,FAG "Sosnoski DM &: J Clin Invest, 81, 1993-1998, 1988 LOC,FAG "Spurr NK, Rooke L: Ann Hum Genet, 55, 217-223, 1991 CLO,SEQ,EXP,EVO "Suzuki S &: JBC, 262, 14080-14085, 1987 CLO,SEQ,EXP,EVO "Suzuki S &: PNAS, 83, N22, 8614-8618, 1986 |
SWI | SWISSPROT: P06756 |
KEY | mem, recp |
CLA | coding, basic |
LOC | 02 q31-32 |
MIM | MIM: 193210 |
SYN | CD51 VNRA |
Ссылки:
- Gene: [17q2132/ITGA2B] integrin, alpha 2b (antigen CD41B); coagulation factor I receptor, alpha subunit; fibrinogen receptor on platelets, alpha subunit; glycoprotein IIb (platelet IIb/IIIa complex); thrombasthenia, Glanzmann-Naegeli type (
- Gene: [16p112/ITGAM] integrin, alpha M (Mac-1a; CD11B; p170); complement component receptor 3, alpha (p170; antigen CD11B); antigen CD11B (macrophage antigen Mac-1-alpha subunit); [CR3A CD11B ]
- Gene: [12q1/ITGA5] integrin, alpha 5 (alpha F; antigen CD49E); fibronectin receptor, alpha polypeptide; [VLA5A CD49E ]
- Gene superfamily: integrins; (ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA4L ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAW ITGAX ITGB1 ITGB1L ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8)