Gene superfamily: integrins; (ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA4L ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAW ITGAX ITGB1 ITGB1L ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8)
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SUM |
Integrins are a large family of cell surface alpha-beta heterodimers involved in cell-cell and cell-extracellular matrix interactions." |
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EVO |
A homology was found between platelet glycoprotein IIB alpha peptides (GEM:17q2132/ITGB3), fibronectin receptor (GEM:12q1/ITGA5), and vitronectin receptor (GEM:02q3/ITGAV). All the three genes belong to the integrin superfamily." |
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REF |
REV,FUN,MEB,EVO "Hynes RO: Cell, 48, 549-554, 1987 |
