Gene: [17q2132/ITGB3] integrin, beta 3 (antigen CD61); fibrinogen receptor on platelets, beta subunit; coagulation factor I receptor, beta subunit; glycoprotein IIIa (platelet GPIIb/IIIa complex); neonatal alloimmune thrombocytopenia; [GP3A CD61 ]
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COM |
ITGB3/GP3A monomer serves as a beta subunit in complex with different alpha subunits to form membrane receptors; their common name is 'integrins' or 'cytoadhesins'; see GEM:17q2132/ITGA2B." |
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REF |
COM,PHE,IDN,FOG "Furihata &: J Clin Invest, 80, 1624-1630, 1987 REV,EVO,SEQ "Hynes RO: Cell, 48, N4, 549-554, 1987 MEB,FUN "Koller &: JBC, 264, N21, 12412-12418, 1989 COM,PHE,IDN,FOG "Kunicki &: J Clin Invest, 67, 717-724, 1981 PRO,GEN,SEQ,EVO "Lanza &: JBC, 265, N30, 18098-18103, 1989 LOC,CYG,MOL "Luo &: CCG, 51, (HGM10), 1036, 1989 PRO,SEQ,LOC "Rosa JP &: Blood, 72, N2, 593-600, 1988 COM,PHE,IDN,FOG "Shibata &: Vox Sang, 51, 334-336, 1986 COM,PHE,IDN,FOG "Von dem Borne &: Vox Sang, 39, 113-120, 1980 |
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KEY |
hem, imm, clot, recp, mem |
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CLA |
coding, basic |
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LOC |
17 q21.32 |
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MIM |
MIM: 173470 |
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SYN |
GP3A CD61 |
Ссылки:
- Gene: [12q1/ITGA5] integrin, alpha 5 (alpha F; antigen CD49E); fibronectin receptor, alpha polypeptide; [VLA5A CD49E ]
- Gene superfamily: integrins; (ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA4L ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAW ITGAX ITGB1 ITGB1L ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8)
