Gene: [07p1/INHBA] inhibin, beta A; activin, beta A; follicle-stimulating hormone (FSH)-releasing protein; erythroid differentiation factor; [EDF ]
FUN | Beta-A inhibin gene encodes one of the chains of inhibins and activins - gonadal glycoprotein hormones - that regulate the secretion of the hypophyseal follicle stimulating hormone (FSH). Beta polypeptide of FSH - follitropin beta - is mapped to Chr 11 (GEM:11p13/FSHB). For more details, see FAM:INH/00.0." |
FAG | [1] Beta-B inhibin
gene is assigned to Chr 2 (GEM:02q1/INHBB).
Beta-C inhibin gene is mapped to Chr 12 (GEM:12q131/INHBC). [2] See also FAM:INH/00.0." |
MOP | [1] Inhibin beta peptides have MM 10.7 kD (94 amino acids) and
have been shown to be unglycosilated. In SDS electrophoresis, the beta
peptide is revealed at the 14-kD band, however this is thought to be a
result of abnormal migration in such a gele. [2] On the alpha peptide structure, see GEM:07p1/INHBA. [3] Structure of inhibin as a whole is described in FAM:INH/00.0." |
REF | LOC,FAG,EVO "Barton &: CCG, 46, (HGM9), 578, 1987 MOP,SEQ "Mason AJ &: BBRC, 135, 957-964, 1986 SEQ "Mason AJ &: Nature, 318, 659-663, 1985 |
SWI | SWISSPROT: P08476 |
KEY | sex, horm |
CLA | coding, basic |
LOC | 07 p15-13 |
MIM | MIM: 147290 |
SYN | EDF |
