Gene: [05q3/PDGFRB] platelet-derived growth factor receptor, beta polypeptide; [PDGFR ]
FAG | See GEM:04q12/PDGFRA. |
EVO | A significant homology has been shown between PDGFR, protooncogene KIT (GEM:04q12/KIT) and macrophage growth factor (GEM:01p/CSF1)." |
REF | IDN,FUN "Bishayee &:
PNAS, 83, N18, 6756-6760, 1986 LOC,MOL,FAG "Francke &: Cold Spring Harbor Symp, 51, 855-866, 1986 PRO,SEQ,EXP "Gronwald RG &: PNAS, 85, N10, 3435-3439, 1988 PEP,SEQ,EVO "Qiu FH &: EMBO J, 7, N4, 1003-1011, 1988 LOC,LIN "Roberts WM &: Cell, 55, 655-661, 1988 REV,FUN,EXP,PAT "Ross R: Lancet, 2, (27 May), 1179-1182, 1989 PEP,SEQ,EVO "Yarden Y &: EMBO J, 6, N11, 3341-3351, 1987 |
SWI | SWISSPROT: P09619 |
KEY | onc, cyk, mem, recp |
CLA | coding, basic |
LOC | 05 q33-35 |
MIM | MIM: 173410 |
SYN | PDGFR |
Ссылки:
- PDGF: эмбриогенез
- Gene: [05q33/CSF1R] colony stimulating factor 1 (macrophage-specific, CSF-M) receptor; McDonough feline sarcoma viral
homolog; friend-murine leukemia virus integration site 2 homolog; anemia macrocytic, refractory (5q-minus syndrome - Gene: [22q1/PDGFB] platelet-derived growth factor, beta polypeptide; simian sarcoma viral
oncogene homolog; [PDGF2 SIS ] - Gene: [12p13/ETV6] ets translocation variant gene 6 (TEL oncogene); [TEL ]
- Gene: [13q12/FLT1] oncogene FLT1 (src/ros/fms-related tyrosine kinase); fms-related tyrosine kinase 1;
- Gene: [08p2/PRLTS] PDGF-receptor beta-like tumor suppressor; platelet-derived growth factor receptor-like; [PDGFRBL ]
- регулятор транскрипции Tel и PDGFR: канцерогенез
