Gene: [17q1/EGFR2] avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 2; oncogene homolog ERBB2 (neuro/glioblastoma derived); protein tyrosine kinase, receptor ERBB2;

COM

On the ERB-like genes see GEM:17q1/THRA.

FAG

This gene is homologous to epidermal growth factor receptor, which gene is located in Chr 7 (GEM:07p12/EGFR1). Another homologues are mapped to Chr 12q13 (GEM:12q13/EGFR3) and Chr 2q24 (GEM:02q34/EGFR4)."

MAP

Loci: GEM:17q112/NF1; GEM:17q1/THRA; FAM:HOXB/17q2; GEM:17q2/NGFR.
[1] See GEM:17q112/NF1."

REF

MOP "Akiyama &: Science, 232, 1644-1646, 1986
MOP "Bargmann CI &: Nature, 319, 226-230, 1986
PRO,SEQ,EXP,EVO "Coussens L &: Science, 230, 1132-1139, 1985
LOC,FAG "Francke &: Cold Spring Harbor Symp, 51, 855-866, 1986
LOC "Fukushige S &: BBRC, 134, 477-483, 1986a
LOC "Fukushige S &: Mol Cell Biol, 6, 955-958, 1986b
LOC "Kaneko &: Jpn J Cancer Res, 78, 16-19, 1987
LOC "Popescu NC &: Genomics, 4, N2, 362-366, 1989
PRO,SEQ,EXP,EVO "Semba K &: PNAS, 82, N19, 6497-6501, 1985
EXP,PAT "Slamon DJ &: Science, 244, (12 May), 707-712, 1989
MAG "Xu WM &: PNAS, 85, N22, 8563-8567, 1988
LOC "Yang-Feng TL &: CCG, 40, (HGM8), 784, 1985

SWI

SWISSPROT: P04626

KEY

onc, mem, recp

CLA

coding, basic

LOC

17 q11.2-12

MIM

MIM: 164870

EZN

ENZYME: 2.7.1.112

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