Gene: [22q1122/BCR1] breakpoint cluster region 1; chronic myelogenous leukemia (CML; Ph'-oncomarker); [PHL BCR ]

COM

Detailed description of the BCR cluster in chr 22 will be available in the next version."

MUT

The BCR locus participates in the formation of the Philadelphia oncomarker (Ph'-chromosome, results from translocation 9q34:22q11; the break in Chr 9 is connected to oncogene ABL: GEM:09q341/ABL1)."

REF

MAP "Budarf M &: Genomics, 3, N2, 168-171, 1988
LOC "Croce &: PNAS, 84, N20, 7174-7178, 1987
REV,PAT,MAF "Kurzrock &: New Engl J Med, 319, N15, 990-998, 1988
GEN,MOP "Lifshtz B &: Oncogene, 2, 113-117, 1988

SWI

 SWISSPROT: P11274

KEY

onc, hem, chr

CLA

coding, basic

LOC

22 q11.22

MIM

 MIM: 151410

SYN

PHL BCR

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